Fructooligosaccharides (FOS): One of the most widely applied prebiotics, FOS has been confirmed as the only all-natural ingredient possessing dual physiological properties of potent bifidogenic factors and water-soluble dietary fiber. Xylooligosaccharides (XOS): Also called xylo-oligosaccharides, they selectively promote the proliferative activity of intestinal bifidobacteria. Their bifidogenic effect is 10-20 times stronger than other polymeric saccharides. Galactooligosaccharides (GOS): When heated with proteins, GOS undergoes the Maillard reaction, making it suitable for processing specialty foods like bread and pastries.
GET A QUOTE1.What is Oligomerization?
Fructooligosaccharides (FOS): One of the most widely applied prebiotics, FOS has been confirmed as the only all-natural ingredient possessing dual physiological properties of potent bifidogenic factors and water-soluble dietary fiber.
Xylooligosaccharides (XOS): Also called xylo-oligosaccharides, they selectively promote the proliferative activity of intestinal bifidobacteria. Their bifidogenic effect is 10-20 times stronger than other polymeric saccharides.
Galactooligosaccharides (GOS): When heated with proteins, GOS undergoes the Maillard reaction, making it suitable for processing specialty foods like bread and pastries.
2.How it Works?
Fructooligosaccharides are difficult to degrade by digestive enzymes in the human gastrointestinal tract. After ingestion, they can increase beneficial bacteria populations by 10-100 times. The organic acids produced (such as acetic acid, lactic acid, propionic acid, and butyric acid) lower intestinal pH, thereby inhibiting the growth of exogenous pathogenic bacteria and indigenous intestinal bacteria like Salmonella. This reduces the production and accumulation of harmful intestinal substances, making FOS an effective category of prebiotics.
Xylooligosaccharides (XOS) are among the most potent bifidogenic agents in polymeric saccharides, exhibiting approximately 20 times greater efficacy than other oligosaccharides. Since no enzymes in the human gastrointestinal tract hydrolyze XOS, they directly reach the colon where bifidobacteria preferentially utilize them. This promotes bifidobacterial proliferation while generating multiple organic acids that lower intestinal pH, inhibit pathogenic bacteria growth, and enable probiotics to flourish - constituting the fundamental mechanism behind XOS's health benefits.
Galactooligosaccharides (GOS) serve as excellent nutrients and effective growth factors for beneficial intestinal bacteria such as bifidobacteria and Lactobacillus acidophilus, improving digestive and absorptive functions in the human gut. Due to underdeveloped digestive systems in newborns, infant formula is routinely supplemented with GOS as a nutritional component.
3.Benefits and Uses
Fructooligosaccharides (FOS):
Prebiotic Effects:
FOS is difficult to degrade by digestive enzymes in the human gastrointestinal tract. Upon ingestion, it increases beneficial bacteria populations by 10–100 times. The organic acids produced (e.g., acetic acid, lactic acid, propionic acid, and butyric acid) lower intestinal pH, inhibiting the growth of exogenous pathogenic bacteria and indigenous intestinal bacteria such as Salmonella, thereby reducing the production and accumulation of harmful intestinal substances. Thus, FOS is recognized as an effective prebiotic.
Promotion of Mineral Absorption:
FOS enhances intestinal absorption of minerals such as calcium and magnesium, benefiting bone health.
Blood Sugar and Cholesterol Control:
As a novel dietary supplement, FOS effectively reduces serum cholesterol, triglycerides, and free fatty acids, improving cardiovascular conditions like hypertension and atherosclerosis caused by hyperlipidemia. In a study by Delzenne, mice fed a diet supplemented with 10% FOS for 8 weeks showed significantly lower plasma total cholesterol levels than the control group, indicating FOS may help regulate lipid metabolism.
Anti-Caries Effect:
Dental caries are associated with Streptococcus mutans-produced glucosyltransferase, which decomposes sucrose into insoluble, adhesive glucans that form dental plaque. Bacteria in plaque ferment sugars to produce acids that erode tooth enamel. Since FOS cannot be cleaved by S. mutans glucosyltransferase, it does not produce adhesive glucans, thus preventing caries.
Anti-Tumor and Immune-Enhancing Effects:
Studies suggest bifidobacteria exhibit anticancer properties, possibly due to immune stimulation by their cells, secretions, and cell wall components. Enhanced immunity helps maintain lymphocyte balance, increasing T and B lymphocytes—central to immune defense—and improving resistance to harmful pathogens. Bifidobacteria also boost antibody-producing cells, activate macrophages, and stimulate the production of secretory IgA (S-IgA), which has 7–10 times the immune potency of other immunoglobulins.
Improved Intestinal Digestion and Absorption:
FOS, a natural component in fruits, vegetables, and honey, resists digestion by gastrointestinal enzymes and acts as an excellent water-soluble dietary fiber. It enhances intestinal mucosal protection, reducing gastrointestinal disorders. FOS intake softens stools (via water retention) and promotes bowel motility. Fermentation by gut probiotics lowers pH, stimulates peristalsis, and increases stool moisture and osmotic pressure. Human trials show that daily intake of 3.0–10.0 g FOS for one week significantly reduces body weight, abdominal fat, and visceral fat.
Xylooligosaccharides (XOS):
Reduction of Toxic Fermentation Byproducts and Harmful Bacterial Enzymes
In vivo and in vitro fecal culture studies demonstrate that within 3 weeks of XOS intake, toxic fermentation byproducts decrease by 44.6% and harmful bacterial enzymes by 40.9%.
Pathogen Inhibition and Diarrhea Prevention
XOS strongly adsorbs pathogens (e.g., Escherichia coli, Salmonella enteritidis, Klebsiella pneumoniae, Aeromonas hydrophila). As XOS resists intestinal enzymatic degradation, it carries adsorbed pathogens out of the gut, preventing colonization and diarrhea.
Constipation Relief
Bifidobacteria metabolize XOS to produce short-chain fatty acids, stimulating peristalsis, increasing fecal moisture, and maintaining osmotic pressure to prevent constipation.
Liver Protection
XOS reduces toxic metabolite formation, alleviating the liver’s detoxification burden.
Serum Cholesterol Reduction
After 2 weeks to 3 months of XOS intake, total serum cholesterol decreases by 20–50 mg/dL. It also increases the HDL-cholesterol ratio in women.
Blood Pressure Regulation
In 46 hyperlipidemic patients, 5 weeks of XOS supplementation reduced diastolic blood pressure by 799.8 Pa (6 mmHg). Diastolic pressure correlates negatively with fecal bifidobacteria abundance.
Immune Enhancement and Anticancer Effects
Bifidobacteria proliferation exerts anticancer effects via immune stimulation by bacterial cells, cell wall components, and secretions.
Synergistic Compatibility
Even minimal dietary XOS intake shows benefits. When co-administered with calcium, XOS enhances calcium absorption, increasing retention by 21% after 7 days of 2% XOS solution intake.
Promotion of Nutrient Synthesis
XOS stimulates endogenous production of B vitamins (B1, B2, B6, B12), niacin, and folate.
Dental Caries Prevention
XOS resists metabolism by cariogenic oral microbes (e.g., Streptococcus spp.), inhibiting plaque formation and tooth decay.
Galactooligosaccharides (GOS):
In nature, GOS exists in trace amounts in animal milk, with slightly higher concentrations in human breast milk. GOS has a pure sweet taste, low caloric value (20–40% the sweetness of sucrose), and strong moisture-retention properties. It exhibits high thermal stability under neutral pH conditions, showing no decomposition after 1 hour at 100°C or 30 minutes at 120°C. When heated with proteins, GOS undergoes the Maillard reaction, making it suitable for processing specialty foods such as bread and pastries.
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A:Yes, our company accepts sample orders.
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A:We will communicate with customers, adopt their suggestions, arrange the most suitable delivery method, and ensure mutual satisfaction.
