Allicin is an organosulfur compound extracted from the bulbs (garlic heads) of Allium sativum in the Alliaceae family, also found in onions and other Allium plants.
GET A QUOTE1.What is Allicin?
Allicin is an organosulfur compound extracted from the bulbs (garlic heads) of Allium sativum in the Alliaceae family, also found in onions and other Allium plants. Its scientific name is diallyl thiosulfinate, with the chemical formula C6H10OS2. The solid form appears as a white to pale yellow free-flowing powder, while the liquid form is a light yellow to brown volatile oily liquid with a strong garlic odor. It decomposes upon distillation, and its aqueous solution forms oily precipitates upon standing. Allicin is insoluble in glycerol and propylene glycol but miscible with ethanol, chloroform, ether, and benzene. It is unstable in alkaline conditions but stable in acidic conditions. The solution rapidly loses potency when heated.
Allicin exhibits potent antibacterial effects, inhibiting various Gram-positive cocci and Gram-negative bacilli at very low concentrations. It also demonstrates inhibitory effects against molds, viruses, protozoa, and pinworms, with particularly notable suppression of Escherichia coli and Shigella. Agriculturally, it serves as an insecticide and fungicide, and is used in feed, food, and pharmaceutical applications.
2.How it Works?
Allicin is an organosulfur compound extracted from garlic, with mechanisms of action spanning multiple biological levels, primarily including:
Antibacterial Effects
Disrupts bacterial membrane structure: Allicin compromises the integrity of bacterial cell membranes, rendering them inactive. This mechanism differs from conventional antibiotics (e.g., those inhibiting DNA replication or cell wall synthesis), functioning as an "adjunct clearance" mode.
Interferes with metabolic functions: Allicin reacts with bacterial cysteine to form crystalline precipitates, disrupting essential thiol groups (SH groups) and causing metabolic dysfunction, thereby inhibiting proliferation.
Broad-spectrum activity: Inhibits Gram-positive/negative bacteria, fungi, viruses, and protozoa, with particularly notable efficacy against Escherichia coli and Shigella.
Immunomodulation and Anti-inflammatory Effects
Enhances nonspecific immunity: Stimulates lymphocytes to secrete interferon and interleukins, increases macrophage numbers, and boosts immune function.
Regulates inflammatory factors: Suppresses pro-inflammatory cytokines (e.g., tumor necrosis factor) while upregulating anti-inflammatory factors, mitigating inflammatory responses.
Antioxidant and Cytoprotective Effects
Reduces oxidative stress, prevents cellular damage, and may delay brain injury and age-related diseases.
Metabolic and Cardiovascular Effects
Hypoglycemic action: Promotes insulin secretion, enhances glucose uptake, and improves diabetic symptoms.
Cardiovascular protection: Lowers cholesterol, inhibits platelet aggregation, and prevents atherosclerosis and thrombosis.
Summary: Allicin's multifaceted mechanisms confer potential in antibacterial applications, immunomodulation, and chronic disease prevention. However, its antibacterial capacity remains adjunctive rather than a complete substitute for antibiotics.
3.Benefits and Uses
In agriculture, it is used as an insecticide and fungicide, as well as in feed, food, and pharmaceutical applications. As a feed additive, it serves the following functions:
(1) Enhances flavor in broiler chickens and soft-shelled turtles. Adding allicin to chicken or turtle feed intensifies the aroma of the meat.
(2) Improves animal survival rates. With its detoxifying, antibacterial, disease-preventing, and therapeutic properties, adding 0.1% allicin to feed for chickens, pigeons, etc. can increase survival rates by 5%-15%.
(3) Stimulates appetite. Allicin increases gastric secretion and gastrointestinal motility, stimulating appetite and aiding digestion. Adding 0.1% allicin to feed enhances palatability. Its distinctive garlic aroma induces appetite, promoting rapid feeding while enhancing gastric secretion and intestinal peristalsis to improve digestion, thereby accelerating growth and significantly improving feed conversion.
(4) Improves feed palatability. Many farmers use less palatable feed ingredients or growth promoters to reduce costs, often resulting in reduced intake or refusal, leading to stunted growth. Allicin supplementation markedly improves feed acceptance and intake. Most animals, especially fish, are strongly attracted to allicin's odor.
(5) Enhances production performance. Allicin not only increases feed intake but also prevents diseases, boosts immunity, optimizes physiological functions, stimulates digestive enzyme secretion, and improves nutrient utilization, thereby enhancing productivity while reducing feed costs. Enzymatically converted to allixin in vivo, it is excreted in waste, inhibiting pest reproduction and improving housing/pond environments.
(6) Antibacterial action: Allicin inhibits pathogens like Shigella and Salmonella, with strong bactericidal effects against Staphylococcus and Streptococcus. Clinically, oral allicin treats enteritis, diarrhea, and anorexia. It suppresses harmful bacteria (E. coli, Salmonella, Staphylococcus aureus, etc.) without affecting beneficial species like Lactobacillus casei.
(7) Detoxification and health maintenance. Significantly reduces toxicity of mercury, cyanides, and nitrites. Animals exhibit glossy coats, robust constitution, disease resistance, and higher survival rates.
(8) Antifungal and antiparasitic. Effectively kills molds, prevents spoilage, inhibits maggot growth, reduces flies in farms, extends feed shelf life, and improves rearing conditions.
(9) Improves meat quality. Treated animals produce meat, eggs, and milk with reduced off-flavors and enhanced taste.
(10) Highly effective against bacterial gill rot, erythroderma, enteritis, and hemorrhages in fish, shrimp, and turtles.
(11) Lowers cholesterol. Inhibits 7α-cholesterol hydroxylase, reducing cholesterol levels in serum, egg yolk, and liver.
(12) Non-toxic, residue-free, and non-antibiotic, it is the ideal additive for producing safe, antibiotic-free products while ensuring human health.
Q:Does the company accept sample orders?
A:Yes, our company accepts sample orders.
Q:What is the minimum order quantity for the company?
A:We do not have a minimum order quantity requirement, we arrange according to the customer's needs.
Q:How to ensure the quality of goods?
A:We have a strict QC/QA management system and strict release procedures, and we will provide all procedures to customers before shipment according to their requirements.
Q:Can we see the product quality before the order is shipped?
A:Of course, we always provide a relative Batach (s) 'COA before shipping.
Q:How will you deliver the goods?
A:We will communicate with customers, adopt their suggestions, arrange the most suitable delivery method, and ensure mutual satisfaction.
