Vitamin K1, also known as phytonadione, phylloquinone, or phytomenadione, is chemically named 2-methyl-3-phytyl-1,4-naphthoquinone. It is a polycyclic aromatic ketone and a fat-soluble vitamin that remains stable in air and moisture but decomposes under sunlight. It is widely present in natural green plants. Vitamin K2 is a fat-soluble vitamin that participates in blood coagulation and plays a role in calcium supplementation. As an essential element for the human body, it belongs to the category of health-supporting pharmaceuticals.
GET A QUOTE1.What is VITAMIN K1/K2?
Vitamin K1, also known as phytonadione, phylloquinone, or phytomenadione, is chemically named 2-methyl-3-phytyl-1,4-naphthoquinone. It is a polycyclic aromatic ketone and a fat-soluble vitamin that remains stable in air and moisture but decomposes under sunlight. It is widely present in natural green plants.
Vitamin K2 is a fat-soluble vitamin that participates in blood coagulation and plays a role in calcium supplementation. As an essential element for the human body, it belongs to the category of health-supporting pharmaceuticals.
2.How it Works?
Vitamin K1 is a yellow, clear, viscous oily liquid. As a fat-soluble vitamin, it is essential for the liver's synthesis of prothrombin, facilitating the conversion of prothrombin precursor to prothrombin. Deficiency leads to hypoprothrombinemia and coagulation disorders. Vitamin K1 is primarily used to prevent and treat bleeding caused by vitamin K deficiency.
Acts as a cofactor in hepatic synthesis of coagulation factors II, VII, IX, and X.
Promotes fibrinogen conversion to fibrin, enhancing plasma fibrin clot elasticity.
Participates in oxidation processes, essential for normal phosphate transfer and high-energy phosphate compound metabolism.
Increases intestinal peristalsis and secretory function while elevating choledochal sphincter tension.
Exhibits significant analgesic effects for certain types of colic.
Vitamin K2 is a member of the vitamin K family. As an essential fat-soluble nutrient, it plays a crucial role in ensuring proper blood clotting and preventing osteoporosis.
Bone Health: Vitamin K2 activates osteocalcin (OCN), facilitating calcium deposition into bones and preventing osteoporosis.
Cardiovascular Protection: By activating matrix Gla protein (MGP), vitamin K2 inhibits vascular calcification and reduces the risk of atherosclerosis.
Anti-inflammatory and Metabolic Regulation: Recent studies suggest that Vitamin K2 may also participate in modulating inflammatory responses and glucose metabolism.
3.Benefits and Uses
Vitamin K1 is an essential substance for prothrombin synthesis in the liver. Deficiency can lead to coagulation disorders. When prothrombin levels in blood are insufficient, blood clotting becomes delayed. Supplementation with appropriate amounts of vitamin K1 promotes hepatic prothrombin synthesis, achieving hemostatic effects.
As a pharmaceutical preparation, vitamin K1 is clinically used for:
Prevention and treatment of hypoprothrombinemia
Vitamin K1 deficiency
Neonatal hemorrhagic disease
Hemorrhage caused by obstructive jaundice, biliary fistula, or chronic diarrhea
Hypoprothrombinemia induced by coumarins or sodium salicylate
Vitamin K1 also exhibits analgesic effects and can relieve bronchospasm. It demonstrates notable efficacy against visceral smooth muscle colic, biliary tract spasm, and intestinal spasm-induced pain. Additionally, vitamin K1 serves as an additive in multivitamin foods and livestock feed.
Vitamin K2 functions include directing calcium into bones, preventing osteoporosis, and improving blood coagulation.
Directing Calcium into Bones
Vitamin K2 facilitates the carboxylation of osteocalcin, converting it into active osteocalcin that promotes calcium ion deposition from blood into bone tissue, thereby enhancing bone calcification.
Preventing Osteoporosis
Vitamin K2 stimulates the production of bone proteins, which combine with calcium to form bone matrix. This process increases bone density, reduces bone fragility, and lowers the risk of osteoporosis.
Improving Blood Coagulation
Vitamin K2 also promotes prothrombin formation, accelerating blood clotting and maintaining normal coagulation time.
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A:Yes, our company accepts sample orders.
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